Squalane
Also known as: Hydrogenated Squalene, Plant-Derived Squalane, Olive Squalane, Sugarcane Squalane
Description
Squalane is the hydrogenated (saturated) form of squalene, a naturally occurring lipid produced by human sebaceous glands. Squalene makes up approximately 12% of human sebum. The hydrogenated form, squalane, is more oxidatively stable and is derived from plant sources such as olives, sugarcane, or amaranth. It is a lightweight, non-comedogenic emollient that closely mimics the skin's natural lipids.
Mechanism of Action
Squalane integrates into the skin's lipid matrix due to its structural similarity to endogenous squalene. It forms a non-occlusive barrier that reduces transepidermal water loss (TEWL) while maintaining skin breathability. Its excellent spreadability and low viscosity allow rapid absorption without a greasy residue. As an antioxidant precursor, it can quench singlet oxygen radicals. It also enhances the penetration of other active ingredients through the stratum corneum.
Indications
- Dry skin
- Dehydrated skin
- Sensitive skin
- Anti-aging (barrier support)
- Post-procedural care
- Adjunct to retinoid therapy
Available Concentrations
Side Effects
- Non-irritating (extremely well tolerated)
- Very rare allergic reaction
Contraindications
- Known hypersensitivity (extremely rare)
Pregnancy Category
Not classified (generally considered safe)