Kojic Acid
Skin Brightening Agent
Also known as: Kojic Acid Dipalmitate, 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one
Description
Kojic acid is a natural metabolite produced by several species of fungi (Aspergillus, Penicillium). It chelates copper at the active site of tyrosinase, inhibiting melanin production. Widely used in Indian and Asian depigmenting products, often in combination with arbutin or vitamin C.
Mechanism of Action
Chelates copper ions at the active site of tyrosinase, rendering the enzyme inactive and suppressing melanogenesis. Also exhibits mild antioxidant and antimicrobial properties. Kojic acid dipalmitate is a lipophilic derivative with improved stability.
Indications
- Melasma
- Post-inflammatory hyperpigmentation
- Age spots
- Uneven skin tone
Available Concentrations
Side Effects
- Contact dermatitis
- Skin irritation and redness
- Increased photosensitivity
Contraindications
- Known hypersensitivity
- Severely irritated or broken skin
Pregnancy Category
Not classified (consult dermatologist)