Benzoyl Peroxide
Organic Peroxide
Also known as: BPO, Dibenzoyl peroxide
Description
Benzoyl peroxide is a potent bactericidal agent widely used in the treatment of acne vulgaris. It is one of the few topical acne agents to which Cutibacterium acnes does not develop resistance.
Mechanism of Action
Releases free-radical oxygen upon contact with the skin, which oxidizes bacterial proteins in Cutibacterium acnes. Also exhibits mild keratolytic and comedolytic activity. Does not induce bacterial resistance.
Indications
- Acne vulgaris (inflammatory and comedonal)
- Folliculitis
- Rosacea (adjunctive)
Available Concentrations
Side Effects
- Dryness
- Erythema
- Peeling
- Contact dermatitis (rare)
- Bleaching of hair, clothing, and fabrics
Contraindications
- Known hypersensitivity to benzoyl peroxide
Pregnancy Category
C