Aloe Vera
Also known as: Aloe Barbadensis Leaf Juice, Aloe Barbadensis Leaf Extract, Aloe
Description
Aloe vera is derived from the inner gel of Aloe barbadensis miller leaves. It contains over 75 active constituents including polysaccharides (acemannan), vitamins, minerals, enzymes, and amino acids. It has been used for centuries in wound healing and is one of the most widely used botanical ingredients in skincare and dermatology.
Mechanism of Action
Acemannan and other polysaccharides stimulate macrophage activity and fibroblast proliferation, accelerating wound healing. Aloe inhibits thromboxane A2 and bradykinin, reducing inflammation and pain. The polysaccharide gel forms a moisture-retaining barrier on the skin surface. Aloin and anthraquinones provide mild antimicrobial activity. Carboxypeptidase in the gel inactivates bradykinin, contributing to anti-inflammatory effects.
Indications
- Sunburn and minor burns
- Wound healing
- Skin hydration
- Post-procedural soothing
- Mild inflammatory skin conditions
- Insect bites
Available Concentrations
Side Effects
- Contact dermatitis (rare)
- Allergic reaction in individuals sensitive to Liliaceae family
Contraindications
- Known allergy to aloe or Liliaceae family plants
Pregnancy Category
Not classified (topical use generally considered safe)